LITERATURE Watch Implications for transplantation

Authors

  • MARIA-LUISA ALEGRE MD, PHD,

  • JONATHAN S. BROMBERG MD, PHD


  • Jonathan S. Bromberg, MD, PhD, Section Editor

Abstract

In recent years, insight into the role of unique immune molecules in preventing infections has been gleaned from the study of patients with recurrent single-agent infections, and the IL-17 pathway is gaining particular attention. This month, Maria-Luisa Alegre and Jonathan Bromberg discuss three recent papers that strongly link a defect in the IL-17 pathway to chronic mucocutaneous candidiasis, a condition thought to be controlled by the adaptive immune system, in contrast to the neutrophil requirement for prevention of invasive candidiasis.

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