Both authors equally contributed as first author.
Lung and Heart Allocation in the United States
Article first published online: 13 SEP 2012
© Copyright 2012 The American Society of Transplantation and the American Society of Transplant Surgeons
American Journal of Transplantation
Volume 12, Issue 12, pages 3213–3234, December 2012
How to Cite
Colvin-Adams, M., Valapour, M., Hertz, M., Heubner, B., Paulson, K., Dhungel, V., Skeans, M. A., Edwards, L., Ghimire, V., Waller, C., Cherikh, W. S., Kasiske, B. L., Snyder, J. J. and Israni, A. K. (2012), Lung and Heart Allocation in the United States. American Journal of Transplantation, 12: 3213–3234. doi: 10.1111/j.1600-6143.2012.04258.x
- Issue published online: 30 NOV 2012
- Article first published online: 13 SEP 2012
- Received 09 July 2012, revised 09 July 2012 and accepted for publication 01 August 2012
- Heart allograft;
- lung allograft;
- organ allocation;
- transplant waiting list;
Lung and heart allocation in the United States has evolved over the past 20–30 years to better serve transplant candidates and improve organ utilization. The current lung allocation policy, based on the Lung Allocation Score, attempts to take into account risk of death on the waiting list and chance of survival posttransplant. This policy is flexible and can be adjusted to improve the predictive ability of the score. Similarly, in response to the changing clinical phenotype of heart transplant candidates, heart allocation policies have evolved to a multitiered algorithm that attempts to prioritize organs to the most infirm, a designation that fluctuates with trends in therapy. The Organ Procurement and Transplantation Network and its committees have been responsive, as demonstrated by recent modifications to pediatric heart allocation and mechanical circulatory support policies and by ongoing efforts to ensure that heart allocation policies are equitable and current. Here we examine the development of US lung and heart allocation policy, evaluate the application of the current policy on clinical practice and explore future directions for lung and heart allocation.