Figure S1: Characterization of NOD.GFP[RIGHTWARDS ARROW]B6.g7 and B6.g7[RIGHTWARDS ARROW]NOD.GFP radiation chimeras. (A) Diabetes incidence of NOD.wt, NOD.GFP and radiation chimeras. (B) After 5 weeks, to allow for hematopoietic cell reconstitution, peripheral blood of full chimeras was assessed by flow cytometry. Full chimerism was assessed in NOD.GFP[RIGHTWARDS ARROW]B6.g7 and B6.g7[RIGHTWARDS ARROW]NOD.GFP mice by gating on peripheral blood live cells and determining the expression of GFP. Lymphocytes of reconstituted B6.g7 mice were 94.0 ± 1.0% NOD.GFP in origin, and reconstituted NOD.GFP mice were 96.3 ± 0.6% B6.g7 in origin. (C) Donor lymphocyte gated T and B cell frequency in peripheral blood at 5 weeks postradiation and BMT.

AJT_4260_sm_suppmat.eps7220KSupporting info item

Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.