In vitro solubility of human pulp tissue in calcium hydroxide and sodium hypochlorite

  1. M. Andersen1,
  2. A. Lund1,
  3. J. O. Andreasen2,*,
  4. F. M. Andreasen1

Article first published online: 27 APR 2006

DOI: 10.1111/j.1600-9657.1992.tb00445.x

Issue

Dental Traumatology

Dental Traumatology

Volume 8, Issue 3, pages 104–108, June 1992

Additional Information

How to Cite

Andersen, M., Lund, A., Andreasen, J. O. and Andreasen, F. M. (1992), In vitro solubility of human pulp tissue in calcium hydroxide and sodium hypochlorite. Dental Traumatology, 8: 104–108. doi: 10.1111/j.1600-9657.1992.tb00445.x

Author Information

  1. 1

    Department of Pediatric Dentistry and Oral and Maxillofacial Surgery, Royal Dental College, Copenhagen, Denmark

  2. 2

    Oral Medicine and Oral Surgery, University Hospital, Copenhagen, Denmark

*J. O. Andreasen, Department of Oral Medicine and Oral Surgery, University Hospital (Rigshospitalet), 18 Tagensvej DK-2200 Copenhagen N, Denmark.

Publication History

  1. Issue published online: 27 APR 2006
  2. Article first published online: 27 APR 2006
  3. Accepted December 1, 1991

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

Get PDF (727K)

Keywords:

  • dental pulp;
  • tissue solubility;
  • calcium hydroxide;
  • sodium hypochlorite

Abstract The tissue solvent capacity of a 2% stabilized sodium hypochlorite solution (Milton®) and a commercial calcium hydroxide solution (Calasept®) was examined under in vitro conditions where autolyzed human pulp fragments weighing approximately 0.0065 g were immersed in these solutions at 37°C for periods of up to 10 days. It appeared that sodium hypochlorite was able to dissolve half the volume of pulp tissue within 1 h and the remaining tissue after 2–2 1/2 h. Calcium hydroxide dissolved half the pulp volume within 2 h, whereas it took 1 week for the remaining tissue to dissolve. These findings support the use of sodium hypochlorite as an irrigation solution during canal preparation and calcium hydroxide as a canal dressing for the purpose of creating a canal free of pulp remnants before root filling.

Get PDF (727K)