Considerations in establishing an oral disease clinical research center


  • ML Barnett,

    1. Clinical Professor, School of Dental Medicine, University at Buffalo and Independent Oral Care Industry Consultant, Princeton, NJ, USA; formerly, Senior Director of Dental Affairs and Technology Development for a Major Multinational Consumer Products Company
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  • BL Pihlstrom

    1. Professor Emeritus, School of Dentistry, University of Minnesota and Independent Oral Health Research Consultant, Bethesda, MD, USA; formerly, Director, Division of Clinical Research and Health Promotion, National Institute of Dental and Craniofacial Research, National Institutes of Health
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ML Barnett, 289 Sayre Drive, Princeton, NJ 08540-5859, USA. Fax: +1 609 243 8909, E-mail:


Oral Diseases (2010) 16, 586–591

High quality clinical research is necessary to improve oral health and translate research findings to the practice of dentistry. This has led many academic institutions to consider establishing a formal clinical research center. This is not a trivial undertaking and requires that the center have an appropriate physical infrastructure, trained investigators with recognized expertise in the planning and conduct of high quality clinical research, and very importantly, a financial plan to assure its long-term sustainability. The purpose of this paper is to provide some guidance and practical advice with respect to factors that should be considered in developing and maintaining a successful oral disease clinical research center.