These two authors contributed equally to the contents of this manuscript.
Oral complications in the treatment of cancer patients
Article first published online: 8 FEB 2011
© 2011 John Wiley & Sons A/S
Volume 17, Issue 6, pages 550–559, September 2011
How to Cite
Mosel, D., Bauer, R., Lynch, D. and Hwang, S. (2011), Oral complications in the treatment of cancer patients. Oral Diseases, 17: 550–559. doi: 10.1111/j.1601-0825.2011.01788.x
- Issue published online: 21 JUL 2011
- Article first published online: 8 FEB 2011
- Accepted manuscript online: 7 JAN 2011 11:39AM EST
- Received 29 December 2010; accepted 30 December 2010
Oral Diseases (2011) 17, 550–559
While treatment for cancer in terms of chemotherapy and radiation therapy have evolved significantly since their inception, both of these cancer treatment modalities, especially if used in combination (e.g., as with head and neck cancers), have a very real potential to result in painful and debilitating adverse effects that clearly decrease quality of life and, potentially, increase mortality due to cancer. Herein, we discuss the prevalence and etiology of three broad categories of oral complications found during the treatment of cancer patients: mucositis, dysgeusia, and infectious disease. Lastly, we present therapeutic options that may be helpful in ameliorating these uncomfortable and, sometimes, life-threatening oral complications.