Role of cigarette filter on the risk of oral cancer: a case–control study in a Chinese population
Article first published online: 10 JUL 2012
© 2012 John Wiley & Sons A/S
Volume 19, Issue 1, pages 80–84, January 2013
How to Cite
Fu, J., Gao, J., Zhang, Z., Zheng, J., Zhong, L., Luo, J. and Xiang, Y. (2013), Role of cigarette filter on the risk of oral cancer: a case–control study in a Chinese population. Oral Diseases, 19: 80–84. doi: 10.1111/j.1601-0825.2012.01959.x
- Issue published online: 7 DEC 2012
- Article first published online: 10 JUL 2012
- Accepted manuscript online: 21 JUN 2012 11:15PM EST
- Received 18 April 2012; revised 28 May 2012; accepted 11 June 2012
- oral squamous cell cancer;
- incidence risk;
- cigarette filter
Oral Diseases (2012) 19, 80–84
Objective: To determine the role of cigarette filter on the incidence risk of oral squamous cell cancer among male smokers in a Chinese population.
Subjects and Methods: A multicentric hospital-based case–control study was applied. Three hundred and nineteen male cases and 428 male controls matching for age (±3 years) were identified from January 2008 to December 2010. Detailed smoking histories were obtained by interviews. Logistic regression model was used to compare the influence of filter and non-filter cigarettes on oral cancer risk.
Results: The adjusted odd ratios (ORs) for oral cancer were 1.30 (95% CI 1.15, 1.48) of filter cigarette smokers, 2.06 (95% CI 1.17, 3.62) of non-filter cigarette smokers, and 1.73 (95% CI 1.33, 2.25) of mixed smokers, as compared with non-smokers. When classified current smokers according to smoking pack year, the ORs of mixed smokers were 2.27 (95% CI 1.06, 4.85) in <20 pack year, 0.81 (95% CI 0.57, 1.14) in 20–39 pack year, and 0.86 (95% CI 0.57, 1.29) in ≥40 pack year, as compared to filter cigarette smokers.
Conclusions: The protective effect against oral cancer of cigarette filter was limited, restricted to smokers of small amount of smoking accumulation. For most smokers, the difference was non-significant between filter and non-filter cigarettes on the risk of developing oral cancer.