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Thermal nociception in adult Drosophila: behavioral characterization and the role of the painless gene
Article first published online: 28 MAR 2006
DOI: 10.1111/j.1601-183X.2006.00213.x
2006 Blackwell Munksgaard
Additional Information
How to Cite
Xu, S. Y., Cang, C. L., Liu, X. F., Peng, Y. Q., Ye, Y. Z., Zhao, Z. Q. and Guo, A. K. (2006), Thermal nociception in adult Drosophila: behavioral characterization and the role of the painless gene. Genes, Brain and Behavior, 5: 602–613. doi: 10.1111/j.1601-183X.2006.00213.x
Publication History
- Issue published online: 31 OCT 2006
- Article first published online: 28 MAR 2006
- Received 9 June 2005, revised 12 January 2006, accepted for publication 16 January 2006
References
- & (1994) Associative odor learning in Drosophila abolished by chemical ablation of mushroom bodies. Science 263, 692–695.
- & (1996) Expression of Drosophila mushroom body mutations in alternative genetic backgrounds: a case study of the mushroom body miniature gene (mbm). Proc Natl Acad Sci USA 93, 9875–9880.
- , & (1959) Analgesimetry and ranking of analgesic drugs by the receptacle method. Arch Int Pharmacodyn Ther 122, 434–447.
- (1967) Behavioral mutants of Drosophila isolated by countercurrent distribution. Proc Natl Acad Sci USA 58, 1112–1119.
- & (1998) The visually-induced jump response of Drosophila melanogaster is sensitive to volatile anesthetics. J Neurogenet 12, 241–251.
- , , , & (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389, 816–824.
- , , , & (1999) A capsaicin-receptor homologue with a high threshold for noxious heat. Nature 398, 436–441.
- , , , , , , , & (2001) The paired homeodomain protein DRG11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord. Neuron 31, 59–73.
- & (1987) Peripheral origins and central modulation of subcutaneous formalin-induced activity of rat dorsal horn neurons. Neurosci Lett 83, 207–211.
- & (1990) Conduction in the giant nerve fiber pathway in temperature-sensitive paralytic mutants of Drosophila. J Neurogenet 6, 207–219.
- & (1996) Altered habituation of an identified escape circuit in Drosophila memory mutants. J Neurosci 16, 3486–3499.
- & (1998) Genetic dissection of functional contributions of specific potassium channel subunits in habituation of an escape circuit in Drosophila. J Neurosci 18, 2254–2267.
- & (1993) Structure of the rat’s behavior in the hot plate test. Behav Brain Res 56, 171–176.
- , , & (2004) Contributions of the anterior cingulate cortex and amygdala to pain- and fear-conditioned place avoidance in rats. Pain 110, 343–353.
- (2000) Developmental Biology, 6th edn. Sinauer Associates, Sunderland.
- , , , , & (1996) Conditioned visual flight orientation in Drosophila: dependence on age, practice, and diet. Learn Mem 3, 49–59.
- , , & (2005) Alterations of membrane properties and effects of d-serine on NMDA-induced current in rat anterior cingulate cortex neurons after monoarthritis. Neurosci Lett 384, 245–249.
- , , , & (1988) A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32, 77–88.
- & (1979) Isolation of anatomical brain mutants of Drosophila by histological means. Z Naturforsch 34c, 143–147.
- & (1984) Vision in Drosophila. Springer-Verlag, Berlin.
- , , , , , , , , , , , , & (2000) Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin. Proc Natl Acad Sci USA 97, 13949–13954.
- & (1974) Genetic manipulation of an abnormal jump response in Drosophila. Genetics 77, 721–739.
- & (1999) Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron 22, 451–461.
- , , , & (1999) EAT-4, a homolog of a mammalian sodium-dependent inorganic phosphate cotransporter, is necessary for glutamatergic neurotransmission in Caenorhabditis elegans. J Neurosci 19, 159–167.
- (1984) The detection of injury and tissue damage. In Wall, P. D. & Melzack, R. (eds) Textbook of pain, Churchill Livingstone, New York, pp. 19–33.
- , & (1998) Disruption of a neuropeptide gene, flp-1, causes multiple behavioral defects in Caenorhabditis elegans. Science 281, 1686–1690.
- & (1996) Behavioral genetics of thermosensation and hygrosensation in Drosophila. Proc Natl Acad Sci USA 93, 6079–6084.
- (2000) Biology of Sensory Systems. John Wiley & Sons Ltd, UK.
- & (1994) An electronic device for monitoring escape behaviour in Musca and Drosophila. J Neurosci Methods 51, 91–94.
- & (1993) A higher control center of locomotor behavior in the Drosophila brain. J Neurosci 13, 1852–1861.
- , , , & (1992) No-bridge of Drosophila melanogaster: portrait of a structural brain mutant of the central complex. J Neurogenet 8, 125–155.
- & (2001) Choice behavior of Drosophila facing contradictory visual cues. Science 294, 1543–1547.
- & (1984) Mutations altering synaptic connectivity between identified neurons in Drosophila. J Neurosci 4, 530–538.
- , , & (2003) Painless, a Drosophila gene essential for nociception. Cell 113, 261–273.
- & (1992) Habituation of the jump reflex to olfactory cues in normal and mutant Drosophila. Soc Neurosci Abstr 18, 942.
- (1984) Methods of testing pain mechanisms in animals. In Wall, P.D. & Melzack, R. (eds) Textbook of Pain, Churchill Livingstone, New York, pp. 178–185.
- & (1999) Thermal avoidance in Caenorhabditis elegans: an approach to the study of nociception. Proc Natl Acad Sci USA 96, 10477–10482.
- & (1991) Basic organization of operant behavior as revealed in Drosophila flight orientation. J Comp Physiol [A] 169, 699–705.
- & (1944) The evaluation of analgesic action of pethidine hydrochloride (Demerol). J Pharmacol Exp Ther 80, 300–307.
- (2001) Two thermosensors in Drosophila have different behavioral functions. J Comp Physiol [A] 187, 235–242.
- , , & (2000) Localization of short-term memory in Drosophila. Science 288, 672–675.

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