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  • Apelt, J., Bigl, M., Wunderlich, P. & Schliebs, R. (2004) Aging-related increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology. Int J Dev Neurosci 22, 475484.
  • Ashley-Koch, A.E., Shao, Y., Rimmler, J.B., Gaskell, P.C., Welsh-Bohmer, K.A., Jackson, C.E., Scott, W.K., Haines, J.L. & Pericak-Vance, M.A. (2005) An autosomal genomic screen for dementia in an extended Amish family. Neurosci Lett 379, 199204.
  • Beal, M.F., Bodis-Wollner, I. & Howell, N. (1997) Mitochondria and Free Radicals in Neurodegenerative Diseases. Wiley-Liss, New York.
  • Blacker, D., Haines, J.L., Rodes, L., Terwedow, H., Go, R.C., Harrell, L.E., Perry, R.T., Bassett, S.S., Chase, G., Meyers, D., Albert, M.S. & Tanzi, R. (1997) ApoE-4 and age at onset of Alzheimer’s disease: the NIMH genetics initiative. Neurology 48, 139147.
  • Blacker, D., Bertram, L., Saunders, A.J. et al. (2003) Results of a high-resolution genome screen of 437 Alzheimer’s disease families. Hum Mol Genet 12, 2332.
  • Christen, Y. (2000) Oxidative stress and Alzheimer disease. Am J Clin Nutr 71, 621S629S.
  • Corder, E.H., Saunders, A.M., Pericak-Vance, M.A. & Roses, A.D. (1995) There is a pathologic relationship between ApoE-epsilon 4 and Alzheimer’s disease. Arch Neurol 52, 650651.
  • Coskun, P.E., Beal, M.F. & Wallace, D.C. (2004) Alzheimer’s brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication. Proc Natl Acad Sci USA 101, 1072610731.
  • Davies, K.J. (1995) Oxidative stress: the paradox of aerobic life. Biochem Soc Symp 61, 131.
  • Dyrks, T., Dyrks, E., Hartmann, T., Masters, C. & Beyreuther, K. (1992) Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation. J Biol Chem 267, 1821018217.
  • Esposito, L., Raber, J., Kekonius, L., Yan, F., Yu, G.Q., Bien-Ly, N., Puolivali, J., Scearce-Levie, K., Masliah, E. & Mucke, L. (2006) Reduction in mitochondrial superoxide dismutase modulates Alzheimer’s disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice. J Neurosci 26, 51675179.
  • Farrer, L.A., Cupples, L.A., Haines, J.L., Hyman, B., Kukull, W.A., Mayeux, R., Myers, R.H., Pericak-Vance, M.A., Risch, N. & Van Duijn, C.M. (1997) Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA 278, 13491356.
  • Fearnhead, N.S., Wilding, J.L., Winney, B., Tonks, S., Bartlett, S., Bicknell, D.C., Tomlinson, I.P., Mortensen, N.J. & Bodmer, W.F. (2004) Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas. Proc Natl Acad Sci USA 101, 1599215997.
  • Fridovich, I. (1978) The biology of oxygen radicals. Science 201, 875880.
  • Fridovich, I. (1995) Superoxide radical and superoxide dismutases. Annu Rev Biochem 64, 97112.
  • Gabbita, S.P., Lovell, M.A., & Markesbery, W.R. (1998) Increased nuclear DNA oxidation in the brain in Alzheimer’s disease. J Neurochem 71, 20342040.
  • Guo, Z., Boekhoudt, G.H. & Boss, J.M. (2003) Role of the intronic enhancer in tumor necrosis factor-mediated induction of manganous superoxide dismutase. J Biol Chem 278, 2357023578.
  • HapMapConsortium (2003) The International HapMap Project. Nature 426, 789796.
  • Heins, N., Malatesta, P., Cecconi, F., Nakafuku, M., Tucker, K.L., Hack, M.A., Chapouton, P., Barde, Y.A. & Gotz, M. (2002) Glial cells generate neurons: the role of the transcription factor Pax6. Nat Neurosci 5, 308315.
  • Hinerfeld, D., Traini, M.D., Weinberger, R.P., Cochran, B., Doctrow, S.R., Harry, J. & Melov, S. (2004) Endogenous mitochondrial oxidative stress: neurodegeneration, proteomic analysis, specific respiratory chain defects, and efficacious antioxidant therapy in superoxide dismutase 2 null mice. J Neurochem 88, 657667.
  • Horvath, S., Xu, X., Lake, S.L., Silverman, E.K., Weiss, S.T. & Laird, N.M. (2004) Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol 26, 6169.
  • Jones, P.L., Ping, D. & Boss, J.M. (1997) Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB. Mol Cell Biol 17, 69706981.
  • Karolchik, D., Baertsch, R., Diekhans, M., Furey, T.S., Hinrichs, A., Lu, Y.T., Roskin, K.M., Schwartz, M., Sugnet, C.W., Thomas, D.J., Weber, R.J., Haussler, D. & Kent, W.J. (2003) The UCSC Genome Browser Database. Nucleic Acids Res 31, 5154.
  • Kehoe, P., Wavrant-De Vrieze, F., Crook, R. et al. (1999) A full genome scan for late onset Alzheimer’s disease. Hum Mol Genet 8, 237245.
  • Kent, W.J., Sugnet, C.W., Furey, T.S., Roskin, K.M., Pringle, T.H., Zahler, A.M. & Haussler, D. (2002) The human genome browser at UCSC. Genome Res 12, 9961006.
  • Krapfenbauer, K., Engidawork, E., Cairns, N., Fountoulakis, M. & Lubec, G. (2003) Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders. Brain Res 967, 152160.
  • Laird, N.M., Horvath, S. & Xu, X. (2000) Implementing a unified approach to family-based tests of association. Genet Epidemiol 19 (Suppl 1): S36S42.
  • Lake, S.L., Blacker, D. & Laird, N.M. (2000) Family-based tests of association in the presence of linkage. Am J Hum Genet 67, 15151525.
  • Lee, J.H., Cheng, R., Santana, V., Williamson, J., Lantigua, R., Medrano, M., Arriaga, A., Stern, Y., Tycko, B., Rogaeva, E., Wakutani, Y., Kawarai, T., St George-Hyslop, P. & Mayeux, R. (2006) Expanded genomewide scan implicates a novel locus at 3q28 among Caribbean Hispanics with familial Alzheimer disease. Arch Neurol 63, 15911598.
  • Li, C., Scott, L.J. & Boehnke, M. (2004) Assessing whether an allele can account in part for a linkage signal: the Genotype-IBD Sharing Test (GIST). Am J Hum Genet 74, 418431.
  • Lunetta, K.L., Faraone, S.V., Biederman, J. & Laird, N.M. (2000) Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions. Am J Hum Genet 66, 605614.
  • Lynn, S., Huang, E.J., Elchuri, S., Naeemuddin, M., Nishinaka, Y., Yodoi, J., Ferriero, D.M., Epstein, C.J. & Huang, T.T. (2005) Selective neuronal vulnerability and inadequate stress response in superoxide dismutase mutant mice. Free Radic Biol Med 38, 817828.
  • Mao, X., Moerman-Herzog, A.M., Wang, W. & Barger, S.W. (2006) Differential transcriptional control of the superoxide dismutase-2 {kappa}B element in neurons and astrocytes. J Biol Chem 281, 3586335872.
  • Markesbery, W.R. (1999) The role of oxidative stress in Alzheimer disease. Arch Neurol 56, 14491452.
  • McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D. & Stadlan, E.M. (1984) Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease. Neurology 34, 939944.
  • Mecocci, P., MacGarvey, U. & Beal, M.F. (1994) Oxidative damage to mitochondrial DNA is increased in Alzheimer’s disease. Ann Neurol 36, 747751.
  • Miranda, S., Opazo, C., Larrondo, L.F., Munoz, F.J., Ruiz, F., Leighton, F. & Inestrosa, N.C. (2000) The role of oxidative stress in the toxicity induced by amyloid beta-peptide in Alzheimer’s disease. Prog Neurobiol 62, 633648.
  • Nacher, J., Varea, E., Blasco-Ibanez, J.M., Castillo-Gomez, E., Crespo, C., Martinez-Guijarro, F.J. & McEwen, B.S. (2005) Expression of the transcription factor Pax 6 in the adult rat dentate gyrus. J Neurosci Res 81, 753761.
  • Nunomura, A., Perry, G., Pappolla, M.A., Wade, R., Hirai, K., Chiba, S. & Smith, M.A. (1999) RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer’s disease. J Neurosci 19, 19591964.
  • Pericak-Vance, M.A., Grubber, J., Bailey, L.R., Hedges, D., West, S., Santoro, L., Kemmerer, B., Hall, J.L., Saunders, A.M., Roses, A.D., Small, G.W., Scott, W.K., Conneally, P.M., Vance, J.M. & Haines, J.L. (2000) Identification of novel genes in late-onset Alzheimer’s disease. Exp Gerontol 35, 13431352.
  • Perry, R.T., Collins, J.S., Harrell, L.E., Acton, R.T. & Go, R.C. (2001) Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controls. Am J Med Genet 105, 332342.
  • Pinteaux, E., Copin, J.C., Ledig, M. & Tholey, G. (1996) Modulation of oxygen-radical-scavenging enzymes by oxidative stress in primary cultures of rat astroglial cells. Dev Neurosci 18, 397404.
  • Pritchard, J.K. & Cox, N.J. (2002) The allelic architecture of human disease genes: common disease-common variant … or not? Hum Mol Genet 11, 24172423.
  • Shimoda-Matsubayashi, S., Matsumine, H., Kobayashi, T., Nakagawa-Hattori, Y., Shimizu, Y. & Mizuno, Y. (1996) Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene. Biochem Biophys Res Commun 226, 561565.
  • Shimoda-Matsubayashi, S., Hattori, T., Matsumine, H., Shinohara, A., Yoritaka, A., Mori, H., Kondo, T., Chiba, M. & Mizuno, Y. (1997) Mn SOD activity and protein in a patient with chromosome 6-linked autosomal recessive parkinsonism in comparison with Parkinson’s disease and control. Neurology 49, 12571262.
  • Smith, M.A. (1997) Morphological aspects of oxidative damage in Alzheimer’s disease. In Beal, M.F., Bodis-Wollner, I. & Howell, N. (eds), Mitochondria and Free Radicals in Neurodegenerative Diseases. Wiley-Liss, New York, pp. 335342.
  • Smith, M.A., Perry, G., Richey, P.L., Sayre, L.M., Anderson, V.E., Beal, M.F. & Kowall, N. (1996) Oxidative damage in Alzheimer’s. Nature 382, 120121.
  • Smith, M.A., Hirai, K., Hsiao, K., Pappolla, M.A., Harris, P.L., Siedlak, S.L., Tabaton, M. & Perry, G. (1998) Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress. J Neurochem 70, 22122215.
  • Szczesny, B., Hazra, T.K., Papaconstantinou, J., Mitra, S. & Boldogh, I. (2003) Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases. Proc Natl Acad Sci USA 100, 1067010675.
  • Tomkins, J., Banner, S.J., McDermott, C.J. & Shaw, P.J. (2001) Mutation screening of manganese superoxide dismutase in amyotrophic lateral sclerosis. Neuroreport 12, 23192322.
  • Varadarajan, S., Yatin, S., Aksenova, M. & Butterfield, D.A. (2000) Review: Alzheimer’s amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity. J Struct Biol 130, 184208.
  • Wan, X.S., Devalaraja, M.N. & St Clair, D.K. (1994) Molecular structure and organization of the human manganese superoxide dismutase gene. DNA Cell Biol 13, 11271136.
  • Warner, B.B., Stuart, L., Gebb, S. & Wispe, J.R. (1996) Redox regulation of manganese superoxide dismutase. Am J Physiol 271, L150L158.
  • Weisiger, R.A. & Fridovich, I. (1973) Mitochondrial superoxide dismutase. Site of synthesis and intramitochondrial localization. J Biol Chem 248, 47934796.
  • Xu, Y., Porntadavity, S. & St Clair, D.K. (2002) Transcriptional regulation of the human manganese superoxide dismutase gene: the role of specificity protein 1 (Sp1) and activating protein-2 (AP-2). Biochem J 362, 401412.
  • Zhang, P., Anglade, P., Hirsch, E.C., Javoy-Agid, F. & Agid, Y. (1994) Distribution of manganese-dependent superoxide dismutase in the human brain. Neuroscience 61, 317330.