Changes in adult neurogenesis in neurodegenerative diseases: cause or consequence?
Article first published online: 3 JAN 2008
2008 Blackwell Publishing Ltd
Genes, Brain and Behavior
Volume 7, Issue Supplement s1, pages 28–42, February 2008
How to Cite
Thompson, A., Boekhoorn, K., Van Dam, A.-M. and Lucassen, P. J. (2008), Changes in adult neurogenesis in neurodegenerative diseases: cause or consequence?. Genes, Brain and Behavior, 7: 28–42. doi: 10.1111/j.1601-183X.2007.00379.x
- Issue published online: 3 JAN 2008
- Article first published online: 3 JAN 2008
- Received 13 July 2007, accepted for publication 12 October 2007
- Alzheimer’s disease;
- amyotrophic lateral sclerosis;
- Huntington’s disease;
- Parkinson’s disease
This review addresses the role of adult hippocampal neurogenesis and stem cells in some of the most common neurodegenerative disorders and their related animal models. We discuss recent literature in relation to Alzheimer’s disease and dementia, Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, alcoholism, ischemia, epilepsy and major depression.