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Figure S1. SDQ hyperactivity scores grouped by genotype for boys and girls aged 4 and 7 years. A: N = 2947, mean (SD) score = 3.6 (2.2); B: N = 2737, mean (SD) score = 2.9 (2.2); C: N = 3182, mean (SD) score = 4.2 (2.3); D: N = 2955 mean (SD) score = 3.7 (2.4).

Figure S2. SDQ conduct scores grouped by genotype for boys and girls aged 4 and 7 years. A: N = 2947, mean (SD) score = 1.9 (1.4); B: N = 2744, mean (SD) score = 1.5 (1.4); C: N = 3182, mean (SD) score = 2.0 (1.4); D: N = 2958, mean (SD) score = 1.7 (1.5).

Table S1: A comparison of adversity measures experienced by children who are still in the study at age 7{\uns}years and those who have dropped out.

Table S2: Derivation of the social deprivation score (0–11)

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