Family-based studies indicate association of Engrailed 2 gene with autism in an Indian population
Article first published online: 24 NOV 2009
© 2009 The Authors. Journal compilation © 2009 Blackwell Publishing Ltd/International Behavioural and Neural Genetics Society
Genes, Brain and Behavior
Volume 9, Issue 2, pages 248–255, March 2010
How to Cite
Sen, B., Surindro Singh, A., Sinha, S., Chatterjee, A., Ahmed, S., Ghosh, S. and Usha, R. (2010), Family-based studies indicate association of Engrailed 2 gene with autism in an Indian population. Genes, Brain and Behavior, 9: 248–255. doi: 10.1111/j.1601-183X.2009.00556.x
- Issue published online: 10 MAR 2010
- Article first published online: 24 NOV 2009
- Received 24 April 2009, revised 24 July 2009, 11 September 2009, 14 October 2009 and 6 November 2009, accepted for publication 7 November 2009
Additional Supporting Information may be found in the online version of this article:
Figure S1: Estimation of linkage disequilibrium (D′) for all the probands (including children from West Bengal and the 30 children belonging to 11 different states) using Haploview. The markers rs6150410, rs34808376, rs3735653 and rs1861973 are denoted as 1, 2, 3 and 4.
Table S1: List of EN2 markers and the specific primer sequences used for PCR amplification of DNA fragments encompassing these polymorphisms.
Table S2: Details of PCR cycling conditions and genotyping analyses.
Table S3: TDT analysis using specific haplotypes formed between markers.
Table S4: HHRR analysis using specific haplotypes formed between markers.
Table S5: TDT and HHRR analyses of rs1861973 considering male probands.
Table S6: Genotype distribution of the 30 non-West Bengal families.
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