Supporting Information

Additional Supporting Information may be found in the online version of this article:

Table S1: Univariate association of 16 SNPs selected from seven circadian clock genes and Li response using Fisher&apos;s exact test. Allele frequencies for the minor allele (A1) are indicated for Li responders and Li nonresponders and nominal P-values (P) and odds ratios (OR) are shown. Uncorrected P < 0.05 was considered nominally statistically significant with 1 df for each analysis.

Table S2: Genes with known or suspected roles in the circadian clock were individually selected from an expression micoarray data set representing over 54 000 transcripts, measured in six LCLs from patients with BD. Expression for the indicated gene was detected by at least one probe. NR1D1 and PER3 were initially not detected by microarray but were readily detected by PCR primers directed toward these transcripts.

As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer-reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.

GBB_725_sm_s1-s2.doc430KSupporting info item

Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.