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Keywords:

  • Adrenalglucocorticoidfunction;
  • acute viral infections

SUMMARY

The hypothalamic pituitary adrenal system was studied in normal Egyptian children and in groups of children with some common viral infections including measles, chicken pox, mumps and poliomyelitis. Results showed a significant rise in plasma 17-OHCS levels in all acute viral infections. ACTH and metyrapone tests revealed that the hypothalamic-pituitary-adrenal axis was functioning adequately. The value of corticosteroids in the management of acute viral infections is discussed in the light of our clinical and laboratory findings.