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Keywords:

  • Infantile colic;
  • Simethicone treatment;
  • crying babies

ABSTRACT. The effect of Simethicone on “colicky” (n=27) infants was tested in a double-blind cross-over study. Three different parameters were used to measure the efficiency of the treatment: interviews, 24-hour records and behavioral observations. No effects of Simethicone on the symptoms of infantile colic could be demonstrated. However, 67 % of the infants improved during the treatment, which could be ascribed to a high-grade placebo-effect.