Anti-inflammatory Properties of Human Milk

Authors

  • A. S. GOLDMAN,

    Corresponding author
    1. Departments of Pediatrics and Human Biological Chemistry and Genetics, the University of Texas Medical Branch, Galveston, Texas, and the Department of Clinical Immunology, University of Göteborg, Göteborg, Sweden
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  • L. W. THORPE,

    1. Departments of Pediatrics and Human Biological Chemistry and Genetics, the University of Texas Medical Branch, Galveston, Texas, and the Department of Clinical Immunology, University of Göteborg, Göteborg, Sweden
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  • R. M. GOLDBLUM,

    1. Departments of Pediatrics and Human Biological Chemistry and Genetics, the University of Texas Medical Branch, Galveston, Texas, and the Department of Clinical Immunology, University of Göteborg, Göteborg, Sweden
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  • L. A. HANSON

    1. Departments of Pediatrics and Human Biological Chemistry and Genetics, the University of Texas Medical Branch, Galveston, Texas, and the Department of Clinical Immunology, University of Göteborg, Göteborg, Sweden
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(A. S. G.) Department of Pediatrics, Division of Immunology/Allergy Child Health Center, The University of Texas Medical Branch Galveston, Texas, USA

Abstract

ABSTRACT. An hypothesis was developed which predicts that human milk protects against infections of the alimentary tract of the breast-fed infant by non-inflammatory mechanisms. Human milk is poor in the initiators and mediators of inflammation and rich in anti-inflammatory agents. Furthermore, many of the anti-inflammatory agents are comparatively resistant to digestive enzymes and therefore might be expected to remain active in the gastrointestinal tract of the recipient. Further studies of these factors in in vivo models will be required to validate the hypothesis.

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