Vitamin D deficiency in Iranian mothers and their neonates: a pilot study

  1. M Bassir1,
  2. S Laborie2,
  3. A Lapillonne3,
  4. O Claris2,
  5. M-C Chappuis4,
  6. BL Salle5,*

Article first published online: 2 JAN 2007

DOI: 10.1111/j.1651-2227.2001.tb00802.x

Issue

Acta Paediatrica

Acta Paediatrica

Volume 90, Issue 5, pages 577–579, May 2001

Additional Information

How to Cite

Bassir, M., Laborie, S., Lapillonne, A., Claris, O., Chappuis, M.-C. and Salle, B. (2001), Vitamin D deficiency in Iranian mothers and their neonates: a pilot study. Acta Paediatrica, 90: 577–579. doi: 10.1111/j.1651-2227.2001.tb00802.x

Author Information

  1. 1

    Department of Pediatrics Shohada Hospital, Tehran, Iran

  2. 2

    Department of Neonatology and Laboratoire des Tissus Calcifies

  3. 3

    Hopital Edouard Herriot, Lyon, France; USDA/ARS Children's Nutrition Research Center

  4. 4

    Department of Laboratoire des Tissus Calcifies

  5. 5

    Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.

*BL Salle, Department of Neonatology, Hopital Edouard Herriot, 5 place ? Arsonval, FR-69437 Lyon cedex 03, France (Tel. +33 4 7211 7646; fax. +33 4 7211 7644, e-mail. salle@univ-lyon1.fr)

Publication History

  1. Issue published online: 2 JAN 2007
  2. Article first published online: 2 JAN 2007

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Keywords:

  • 25-hydroxyvitamin D;
  • rickets;
  • osteomalacia;
  • sunshine exposure

We conducted a pilot study to assess the prevalence of hypovitaminosis D among Iranian women and their newborns. Blood samples were taken from 50 mothers (age 16–40 yr) and their neonates at term delivery in the largest Tehran hospital. The results showed that 80% of the women had 25-hydroxyvitamin D (25-OHD) concentrations of less than 25 nmol/l. Mean maternal plasma calcium and phosphatase alkaline concentrations were in the normal range. The mean maternal serum immunoreactive parathyroid hormone concentration of women with hypovitaminosis D (i.e., 25-OHD levels < 25 nmol/l) was above normal range and significantly different from that of women without hypovitaminosis D.

Conclusion: The mean cord serum 25-OHD concentration was very low (4.94 ± 9.4 nmol/l) and that of infants of mother with hypovitaminosis D were almost undetectable (1.2 ± 1.2 nmol/l).

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