Aim: To evaluate whether intrauterine growth retardation (IUGR) protects against the development of allergy. Methods: A case-control study of 1515 subjects (15–25 y), of whom 430 were cases (birthweight/length below – 2 SD for gestational age). Birth data were from the national birth register. The frequencies of allergic diseases were evaluated by questionnaire. Results: For the 950 who replied, the frequencies of allergic diseases were similar in cases and controls.
Conclusion: IUGR does not protect against the development of allergy.