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Vincristine, an efficacious alternative for diffuse neonatal haemangiomatosis

Authors


Correspondence
Máximo Vento, PhD, MD, Professor in Pediatrics, Servicio de Neonatología, Hospital Universitario Materno Infantil La Fe, Avenida de Campanar 21, E46009 Valencia, Spain. Tel: + 34-96-3862791 | Fax: +34-96-1973408 | Email: maximo.vento@uv.es

Abstract

Diffuse neonatal haemangiomatosis (DNH) is an uncommon condition characterized by multiple cutaneous and visceral haemangiomas frequently causing severe complications. Corticosteroids constitute the first therapeutic line; however, when they fail, other alternatives are available, provided possible side effects are closely monitored during and after treatment. We present a case of life-threatening DNH, non-responsive to corticosteroids, successfully treated with Vincristine with minor side effects. We conclude that Vincristine is a valid alternative in corticosteroid-resistant DNH.

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