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Current controversies in perinatal steroid therapy


Eric S Shinwell, Department of Neonatology, Kaplan Medical Center, PO Box 1, Rehovot 76100, Israel. Tel: +972-8944-1218 | Fax: +972-8944-1768 | Email:


Few therapies in perinatal medicine have created as much controversy as corticosteroids. Despite five decades of extensive research and practice, major areas of uncertainty remain. In this article, we review the most current evidence on both antenatal and postnatal therapy.

Conclusion: Overall, it is clear that we must continue to investigate the most appropriate doses of the ideal preparation in the most appropriate target populations before we can let the steroid issues rest.