High-risk human papilloma viruses (HPVs) were not detected in the benign skin lesions of a small number of children
Article first published online: 27 AUG 2008
©2008 The Author(s)/Journal Compilation ©2008 Foundation Acta Pædiatrica/Acta Pædiatrica
Volume 97, Issue 12, pages 1669–1671, December 2008
How to Cite
Mammas, I., Sourvinos, G., Michael, C. and Spandidos, D. (2008), High-risk human papilloma viruses (HPVs) were not detected in the benign skin lesions of a small number of children. Acta Paediatrica, 97: 1669–1671. doi: 10.1111/j.1651-2227.2008.01004.x
- Issue published online: 6 NOV 2008
- Article first published online: 27 AUG 2008
- Received 14 May 2008; revised 23 July 2008; accepted 29 July 2008.
- ‘High-risk’ HPVs;
- HPV 16;
- HPV 18;
- Human papilloma virus (HPV);
Aim: Human papilloma virus (HPV) can be transmitted via sexual as well as nonsexual routes. Recently, ‘high-risk’ HPVs were detected in the oral mucosa of children in whose cases there was no suspicion of sexual abuse. This implies that HPV 16 and 18 have additional nonsexual modes of transmission in childhood, such as vertical transmission and autoinoculation.
Methods: Using polymerase chain reaction (PCR) assays, we examined the skin tissues of 12 children with benign skin lesions, aged between 6 and 13 years, for the presence of HPV.
Results: Among 12 biopsy skin specimens, no ‘high-risk’ HPV DNA was detected. Specific PCRs for HPV DNA 16 and 18 were also negative.
Conclusion: This preliminary case-control study indicates the absence of mucosal ‘high-risk’ HPV types in the benign skin lesions of children.