Patterns of food and aeroallergen sensitization in childhood eczema
Article first published online: 15 SEP 2008
©2008 The Author(s)/Journal Compilation ©2008 Foundation Acta Pædiatrica/Acta Pædiatrica
Volume 97, Issue 12, pages 1734–1737, December 2008
How to Cite
Hon, K.-L. E., Leung, T.-f., Ching, G., Chow, C.-m., Luk, V., Ko, W.-s. F. and Ng, P.-C. (2008), Patterns of food and aeroallergen sensitization in childhood eczema. Acta Paediatrica, 97: 1734–1737. doi: 10.1111/j.1651-2227.2008.01034.x
- Issue published online: 6 NOV 2008
- Article first published online: 15 SEP 2008
- Received 13 July 2008; revised 3 August 2008; accepted 20 August 2008.
- Atopic dermatitis;
Aim: To compare the patterns of Type 1 sensitization of common food and aeroallergens among infants and older patients with atopic dermatitis (AD).
Methods: All skin prick tests (SPTs) performed over a 6-month period were examined, and patients with urticaria were used for comparison.
Results: Dust mite was the most common aeroallergen and dog dander the least common. Egg white was the most common food allergen and beef the least common. Dust mite and peanut sensitization was more prevalent in AD than in urticaria. Dust mite sensitization was more prevalent in older children than infants with AD. Cow's milk sensitization only occurred in one-tenth of these patients. Prevalence of sensitization to common aeroallergens, but not food allergens, was generally higher in children beyond 5 years of age.
Conclusion: Milk sensitization is far less prevalent than egg white, and the prevalence does not change beyond infancy. There is no significant change in prevalence in many of the common food allergens beyond infancy. Many infants with AD develop eczema before they show atopy to the common food and aeroallergens. The SPT information is useful in reassuring parents of the unlikelihood of severe Type 1 immediate IgE reaction to some of the common food and aeroallergens, so that empirical and multiple food avoidance/restriction can be avoided.