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Bronchomalacia occurring in monozygotic twins – further information about its inheritance

Authors

  • Malcolm Brodlie,

    1. Department of Respiratory Paediatrics, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Newcastle upon Tyne, UK
    2. Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK
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  • David A Spencer

    1. Department of Respiratory Paediatrics, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Newcastle upon Tyne, UK
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Dr. Malcolm Brodlie, Room 230, Sir William Leech Centre for Lung Research, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK. Tel: +44-191-2336161 | Fax: +44-191-233-1417 | Email: m.j.brodlie@ncl.ac.uk

Abstract

We report left main-stem bronchomalacia occurring in monozygotic twins that became symptomatic during infancy. This phenomenon has not previously been reported to occur in twins. Little is known about the aetiology of primary bronchomalacia, but this occurrence suggests that there may be a significant genetic component in some cases.

Conclusion:  Left main-stem bronchomalacia occurring in monozygotic twins suggests that there may be a significant genetic component in some cases and provides further information about the inheritance of this condition.

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