New technologies extend the scope of newborn blood-spot screening, but old problems remain unresolved
Article first published online: 29 OCT 2010
© 2010 The Author(s)/Journal Compilation © 2010 Foundation Acta Pædiatrica
Volume 99, Issue 12, pages 1766–1772, December 2010
How to Cite
Pollitt, R. J. (2010), New technologies extend the scope of newborn blood-spot screening, but old problems remain unresolved. Acta Paediatrica, 99: 1766–1772. doi: 10.1111/j.1651-2227.2010.01950.x
- Issue published online: 29 OCT 2010
- Article first published online: 29 OCT 2010
- Received 1 June 2010; revised 5 July 2010; accepted 7 July 2010.
- Cystic fibrosis;
- Newborn screening;
- Tandem mass spectrometry
The potential of newborn blood-spot screening is expanding rapidly with the development of new analytical techniques and treatment methods. At the same time, some existing programmes, particularly that for congenital hypothyroidism, are coming under scrutiny because of suspicion that they are being shaped by analytical performance rather than evidence of clinical need. Screening policy varies greatly from country to country.
Conclusion: Ethical and political considerations may sometimes override formal scientific decision models.