Elevated nocturnal blood pressure and heart rate in adolescent chronic fatigue syndrome
Article first published online: 17 NOV 2010
© 2010 The Author(s)/Acta Pædiatrica © 2010 Foundation Acta Pædiatrica
Volume 100, Issue 2, pages 289–292, February 2011
How to Cite
Hurum, H., Sulheim, D., Thaulow, E. and Wyller, V. B. (2011), Elevated nocturnal blood pressure and heart rate in adolescent chronic fatigue syndrome. Acta Paediatrica, 100: 289–292. doi: 10.1111/j.1651-2227.2010.02073.x
- Issue published online: 10 JAN 2011
- Article first published online: 17 NOV 2010
- Accepted manuscript online: 9 NOV 2010 06:47AM EST
- Received 23 August 2010; revised 15 October 2010; accepted 22 October 2010.
- Ambulatory blood pressure recording;
- Autonomic nervous system;
- Chronic fatigue syndrome
Aim: To compare ambulatory recordings of heart rate (HR) and blood pressure in adolescents with chronic fatigue syndrome (CFS) and healthy controls. We hypothesized both HR and blood pressure to be elevated among CFS patients.
Methods: Forty-four CFS patients aged 12–18 years were recruited from our paediatric outpatient clinic. The controls were 52 healthy adolescents having similar distribution of age and gender. 24-h ambulatory blood pressure and HR were recorded using a validated, portable oscillometric device.
Results: At night (sleep), HR, mean arterial blood pressure and diastolic blood pressure were significantly higher in CFS patients as compared with controls (p < 0.01). During daytime, HR was significantly higher among CFS patients (p < 0.05), whereas blood pressures were equal among the two groups.
Conclusions: The findings support previous experimental evidence of sympathetic predominance of cardiovascular control in adolescent CFS patients. Also, the findings prompt increased focus on cardiovascular risk assessment and suggest a possible target for therapeutic intervention.