Anaphylactic reactions to measles–mumps–rubella vaccine in three children with allergies to hen’s egg and cow’s milk

Authors


Cansin Sackesen, M.D., Faculty of Medicine, Pediatric Allergy and Asthma Unit, Hacettepe University, 06100 Ankara, Turkey. Tel: +90-312-324 2511 | Fax: +90-312-311 2357 | Email: (csackesen@yahoo.com)

Abstract

Aim:  Allergies to hen’s egg and cow’s milk are the most frequent food allergies in infancy and childhood. Current guidelines recommend safe administration of measles–mumps–rubella (MMR) vaccine in egg allergic patients.

Methods:  We present three cases of anaphylaxis that we encountered after MMR vaccination in children sensitized to hen’s egg and cow’s milk.

Results:  Even though MMR vaccine is generally known to be safe in children with egg allergy, there may still be isolated cases of anaphylaxis.

Conclusion:  Therefore, we recommend that all children not only those who were sensitized to foods should receive the MMR vaccination in a setting that is equipped to deal with anaphylactic reactions. As stated by WHO in immunization safety surveillance, ‘Each vaccinator must have an emergency kit with adrenaline, and be familiar with its dosage and administration’.

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