Paradigm shift in consciousness research: the child′s self-awareness and abnormalities in autism, ADHD and schizophrenia
Article first published online: 23 SEP 2011
© 2011 The Author(s)/Acta Pædiatrica © 2011 Foundation Acta Pædiatrica
Volume 101, Issue 2, pages 112–119, February 2012
How to Cite
Lou, H. C. (2012), Paradigm shift in consciousness research: the child′s self-awareness and abnormalities in autism, ADHD and schizophrenia. Acta Paediatrica, 101: 112–119. doi: 10.1111/j.1651-2227.2011.02456.x
- Issue published online: 9 JAN 2012
- Article first published online: 23 SEP 2011
- Accepted manuscript online: 29 AUG 2011 12:09PM EST
- Received 29 June 2011; revised 12 August 2011; accepted 26 August 2011.
- Conscious experience;
Self-awareness is a pivotal component of any conscious experience and conscious self-regulation of behaviour. A paralimbic network is active, specific and causal in self-awareness. Its regions interact by gamma synchrony. Gamma synchrony develops throughout infancy, childhood and adolescence into adulthood and is regulated by dopamine and other neurotransmitters via GABA interneurons. Major derailments of this network and self-awareness occur in developmental disorders of conscious self-regulation like autism, attention deficit hyperactivity disorder (ADHD) and schizophrenia.
Conclusion: Recent research on conscious experience is no longer limited to the study of neural ‘correlations’ but is increasingly lending itself to the study of causality. This paradigm shift opens new perspectives for understanding the neural mechanisms of the developing self and the causal effects of their disturbance in developmental disorders.