A review of a paediatric emergency department vaccination programme for patients at risk of allergy/anaphylaxis
Article first published online: 12 JUN 2012
© 2012 The Author(s)/Acta Pædiatrica © 2012 Foundation Acta Pædiatrica
Volume 101, Issue 9, pages 941–945, September 2012
How to Cite
Cronin, J., Scorr, A., Russell, S., McCoy, S., Walsh, S. and O’Sullivan, R. (2012), A review of a paediatric emergency department vaccination programme for patients at risk of allergy/anaphylaxis. Acta Paediatrica, 101: 941–945. doi: 10.1111/j.1651-2227.2012.02737.x
- Issue published online: 3 AUG 2012
- Article first published online: 12 JUN 2012
- Accepted manuscript online: 22 MAY 2012 02:00AM EST
- Received 25 January 2012; revised 30 May 2012; accepted 14 May 2012.
- Paediatric emergency department;
Aim: We sought to review the clinical outcomes of patients referred to our emergency department (ED) vaccination service for children with a history of allergy or anaphylaxis or in whom there was a concern of a significant adverse reaction.
Methods: This was a prospective observational cohort study set in an urban tertiary Paediatric ED. All attendances for any childhood vaccination for a 5-year period (from January 1, 2006 to December 31, 2010) were included. Our primary outcome measure was any adverse reaction as a result of the vaccine administered.
Results: A total of 446 vaccines were administered during the study period in 374 patients. Of these vaccinations, 310 (69.5%) were Measles, Mumps, Rubella (MMR). The majority of patients (348, 93%) were referred from the community. Suspected egg allergy was the reason for the majority of referrals for MMR (261/310 (84.2%)). Only six patients (1.3%) experienced an immediate reaction to a vaccination. All reactions were minor.
Conclusion: This is one of the largest studies looking at childhood vaccinations performed in a hospital setting for children who are ‘at risk’ of allergy, anaphylaxis or hypersensitivity. A significant number of referrals were unwarranted and the majority could have been safely managed in the community.