INFLUENCE OF INTESTINAL STRANGULATION FLUID FROM RATS ON THE SERUM SENSITIVITY OF E. COLI

Authors

  • Arne Trippestad,

    1. Institute for Surgical Research and Kaptein W. Wilhelmsen og Frues Bakteriologiske Institutt, University Hospital, Rikshospitalet, Oslo, Norway
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  • Tore Midtvedt

    1. Institute for Surgical Research and Kaptein W. Wilhelmsen og Frues Bakteriologiske Institutt, University Hospital, Rikshospitalet, Oslo, Norway
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Abstract

The results presented indicate that substances with different activities on E. coli are present in exudate produced in rats during the later stages of intestinal strangulation obstruction. The sterile filtered exudate contains substances which inhibit the bactericidal activity of normal serum on the bacteria. These substances do not appear to be adsorbed to the bacteria. Other substances in the filtrate stimulate the deleterious effect of serum on E. coli. These substances are probably adsorbed to the bacteria.

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