Laboratory of Pediatric Pathology, Rigshospitalet, University Hospital, DK-2100 Copenhagen, Denmark.
THE ADRENAL GLANDS IN CYSTIC FIBROSIS
Morphology Correlated with Clinical Findings
Article first published online: 15 AUG 2009
1972 Acta Pathologica, Microbiologica et Immunologica Scandinavica
Acta Pathologica Microbiologica Scandinavica Section A Pathology
Volume 80A, Issue 5, pages 615–620, July 1972
How to Cite
Bech, K. and Nielsen, E. L. (1972), THE ADRENAL GLANDS IN CYSTIC FIBROSIS. Acta Pathologica Microbiologica Scandinavica Section A Pathology, 80A: 615–620. doi: 10.1111/j.1699-0463.1972.tb00324.x
- Issue published online: 15 AUG 2009
- Article first published online: 15 AUG 2009
- Received 20.iii.72
The findings obtained by morphological investigation of the adrenal glands from 23 patients with cystic fibrosis (CF), have been compared with the findings in 46 controls. In 14 patients with CF, changes in the form of necrosis and/or haemorrhage in the permanent cortex were found and, in addition, in 3 of these there was an accumulation of lipid. The changes were independent of age. In 8 control patients, similar changes localized to the same site were found, but almost exclusively in older children. No correlation was found between these changes and the clinical course of the disease. A number of different investigations suggesting changes in the steroid metabolism in CF are reported.