ULTRASTRUCTURE OF A MEASLES-CARRIER HUMAN CELL LINE

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Abstract

Electron microscopic studies were conducted on cultured monolayers of human cells (LU 106) persistently infected with the Edmonston strain of measles virus. Viral nucleocapsids were detectable in the cytoplasm and less often in the nucleus. The aspects of virus/cell interrelationships described and discussed are: (a) the occurrence of viral materials in metaphase cells, (b) the appearance of degenerating cytoplasms and nuclei, (c) the occurrence of microtubules in cellular projections that contained aligned nucleocapsids, and (d) the release of nucleocapsids through the rupture of the cell membrane.

Ancillary