Implant Placement in Patients with Oral Bisphosphonate Therapy: A Case Series

  1. Ghasem Omati Shabestari DDS, MS1,
  2. Yadollah Soleimani Shayesteh DDS, MS2,
  3. Arash Khojasteh DMD, MS3,
  4. Marzieh Alikhasi DDS, MS4,
  5. Neda Moslemi DDS, MS5,
  6. Amin Aminian DDS6,
  7. Reza Masaeli DDS7,
  8. Behnam Eslami DDS, MS8,
  9. Nathaniel S. Treister DMD, DMSc9

Article first published online: 28 APR 2009

DOI: 10.1111/j.1708-8208.2009.00150.x

Issue

Clinical Implant Dentistry and Related Research

Clinical Implant Dentistry and Related Research

Volume 12, Issue 3, pages 175–180, September 2010

Additional Information

How to Cite

Shabestari, G. O., Shayesteh, Y. S., Khojasteh, A., Alikhasi, M., Moslemi, N., Aminian, A., Masaeli, R., Eslami, B. and Treister, N. S. (2010), Implant Placement in Patients with Oral Bisphosphonate Therapy: A Case Series. Clinical Implant Dentistry and Related Research, 12: 175–180. doi: 10.1111/j.1708-8208.2009.00150.x

Author Information

  1. 1

    Assistant professor, Tehran University of Medical Science, Prosthodontics and Dental Research Center, Tehran, Iran;

  2. 2

    associate professor, Tehran University of Medical Science, Periodontics and Dental Research Center, Tehran, Iran;

  3. 3

    assistant professor, Beheshti University of Medical Sciences, Oral and Maxillofacial Surgery, Taleghani Hospital, Tehran, Iran;

  4. 4

    assistant professor, Tehran University of Medical Science, Prosthodontics and Dental Research Center, Tehran, Iran;

  5. 5

    assistant professor, School of Dentistry, Tehran University of Medical Sciences, Department of Periodontics, Tehran, Iran;

  6. 6

    resident of orthodontics, Shahid Beheshti University of Medical Sciences, Department of Orthodontics, Tehran, Iran;

  7. 7

    dentist, private practice, Tehran, Iran;

  8. 8

    research fellow, Harvard School of Dental Medicine, Department of Oral Medicine, Infection and Immunity, Boston, MA, USA;

  9. 9

    assistant professor, Harvard School of Dental Medicine, Department of Oral Medicine, Infection and Immunity, Boston, MA, USA

*Dr. Marzieh Alikhasi, Department of Prosthodontics and Dental Research Center, School of Dentistry, Medical Sciences/University of Tehran, Ghods St., Enghelab St., Tehran, Iran; e-mail: m_alikhasi@yahoo.com

Publication History

  1. Issue published online: 2 AUG 2010
  2. Article first published online: 28 APR 2009

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Keywords:

  • bisphosphonate;
  • case series;
  • implant;
  • survival

ABSTRACT

Background: Although the effect of bisphosphonates on dental implant osseointegration is not clear, dental implant failures attributable to oral bisphosphonate therapy have been reported in patients with osteoporosis.

Purpose: The aim of this study was to evaluate implant survival in patients with a history of bisphosphonate therapy in a retrospective survey.

Materials and Methods: A total of 46 ITI implants placed in 21 osteoporotic patients (females; average age 53 years, range 42–79 years) were evaluated with regard to probing depth, mobility, thread exposure, and bleeding on probing. All patients were under oral bisphosphonate therapy.

Results: None of implants showed mobility and all patients could be considered free from peri-implantitis. Time of bisphosphonate therapy before and after implant insertion showed no statistically significant influence on PD, BOP, and TE. Likewise, implant location, prosthetic type, and opposing dentition had no statistically significant influence on the clinical and radiological parameters of implants.

Conclusion: Within the limitations of this study, it could be concluded that neither being on oral bisphosphonate treatment before implant placement nor starting bisphosphonate therapy after implant installation might jeopardize the successful osseointegration and clinical and radiographic condition of the implants.

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