Timing of Implant Placement and Augmentation with Bone Replacement Material: Clinical Assessment at 8 and 16 Months

Authors

  • Zvi Artzi DMD,

    Corresponding author
    1. Associate professor and director of Graduate Periodontics, Department of Periodontology and Dental Implantology, School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel;
    Search for more papers by this author
  • Carlos E. Nemcovsky DMD,

    1. associate professor, Department of Periodontology and Dental Implantology, School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel;
    Search for more papers by this author
  • Haim Tal DMD, PhD,

    1. professor and chairman, Department of Periodontology and Dental Implantology, School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel;
    Search for more papers by this author
  • Avital Kozlovsky DMD

    1. associate professor, Department of Periodontology and Dental Implantology, School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel
    Search for more papers by this author

  • This study was funded by a grant of the Osteology Foundation.

Prof. Zvi Artzi, DMD, Department of Periodontology, School of Dental Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel; e-mail: zviartzi@tau.ac.il

ABSTRACT

Purpose: The purpose of this study is to evaluate implants placed at different times of bone augmentation.

Materials and Methods: Four implants were placed in seven dogs: one at a 6-month bovine mineral grafted site (6-month Bio-Oss® grafted site [6mBio]), one at a grafted membrane-protected simultaneously augmented (Fresh Bio-Oss® grafted site [FrBio]) site, one at a clotted (nongrafted clotted membrane-protected site [Clot]) membrane-protected site, and one at a pristine (nongrafted uncovered site [Cont]) site. Implants were exposed after 6 months. The same protocol was repeated on the contralateral side, at a delay of 8 months. Peri-implant care was performed throughout the hygienic phase (2 and 10 months, respectively) every 48 to 72 hours. Probing depth and bleeding on probing were recorded. Implant stability was determined by a Periotest® (Medizintechnik Gulden, Modautal, Germany). Statistical analysis was conducted using analysis of variance with repeated measures.

Results: Average probing depth at the simultaneously grafted sites was 2.21 mm and 2.03 mm at 8 and 16 months, respectively. At the 6-month grafted sites, it was 1.96 mm and 1.57 mm. At the Clot sites, it was 2.68 mm and 2.07 mm, and 2.21 mm and 1.82 mm at the Cont sites, respectively. The average bleeding on probing was 0.50 and 0.42 at the FrBio sites, and 0.35 and 0.07 at the 6mBio sites during the respective periods. At the Clot sites, it was 0.50 and 0.28, and at the Cont sites, 0.43 and 0.21, respectively. Probing depth significantly reduced over the time at 6mBio, Clot, and Cont sites (p < .03). Average implant stability score at the FrBio sites was −0.24 and −0.27, and −0.50 and −0.46 at the 6mBio sites, at 8 and 16 months, respectively. At the Clot sites, it was −0.35 and −0.46. Cont sites averaged −0.37 at both periods. Implant stability was significantly higher (p < .005) comparing 6mBio over FrBio, 6mBio over Cont, and Clot over FrBio sites.

Conclusions: Immediate and delayed augmentations are safe modes. Probing depth and bleeding indices gradually improved along time. Implant stability was higher at the delayed mode.

Ancillary