Underdiagnosis of Chikungunya Virus Infections in Symptomatic Dutch Travelers Returning From the Indian Ocean Area

Authors

  • Chantal B.E.M. Reusken PhD,

    Corresponding author
    • Netherlands Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
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  • Jacinta Bakker TA,

    1. Netherlands Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
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  • Johan H.J. Reimerink TA,

    1. Netherlands Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
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  • Hana Zelena PhD,

    1. National Reference Centre for Arboviruses, Institute for Public Health, Ostrava, The Czech Republic
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  • Marion G.P. Koopmans DVM, PhD

    1. Netherlands Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    2. Department of Virology, Erasmus MC, Rotterdam, The Netherlands
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Corresponding Author: Chantal Reusken, PhD, Netherlands Centre for Infectious Disease Control, National Institute for Public Health and the Environment, P.O. Box 1, 3720BA Bilthoven, The Netherlands. E-mail: Chantal.Reusken@RIVM.nl

Abstract

A putative underdiagnosis of clinical chikungunya virus infection in Dutch travelers to the Indian Ocean area was addressed by retrospective screening of all sera for which requested dengue virus serology was negative in the period 2007 to 2010. Evidence for a recent infection was observed in 6.5% of 107 patients, indicating a substantial underdiagnosis and the need for increased awareness among physicians.

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