Dr. Cronin's current address in University of Pennsylvania, School of Veterinary Medicine, 3850 Spruce St., Philadelphia, PA 19104.
RADIATION THERAPY AND SURGERY FOR FIBROSARCOMA IN 33 CATS
Article first published online: 23 MAY 2005
Veterinary Radiology & Ultrasound
Volume 39, Issue 1, pages 51–56, January 1998
How to Cite
Cronin, K., Page, R. L., Spodnick, G., Dodge, R., HARDIE, E. N., PRICE, G. S., RUSLANDER, D. and Thrall, D. E. (1998), RADIATION THERAPY AND SURGERY FOR FIBROSARCOMA IN 33 CATS. Veterinary Radiology & Ultrasound, 39: 51–56. doi: 10.1111/j.1740-8261.1998.tb00325.x
- Issue published online: 23 MAY 2005
- Article first published online: 23 MAY 2005
- Received August 29, 1996; accepted for publication January 22, 1997.
Thirty-three cats with histologically confirmed fibrosarcomas were treated with radiation therapy followed by surgery. The median (95% confidence interval) disease free interval and overall survival were 398 (261,924) and 600 (lower limit 515) days, respectively. There were 19 treatment failures; 11 cats had only local recurrence, 4 cats developed metastatic disease, 3 cats had local recurrence followed by metastasis, and 1 cat developed simultaneous local and distant disease. Twelve cats are alive and discase free. Two cats died without evidence of treatment failure. The presence of tumor cells at the margin of resected tissue after radiation was the only variable which influenced treatment success. The median (95% confidence interval) disease free interval in 5 cats with tumor cells at the margin of the resected specimen was 112 (94,150) days versus 700 (lower limit 328) days for 26 cats with negative tumor margins, p<0.0001. We did not identify a relationship between tumor volume, number of prior tumor excisions, concomitant use of chemotherapy or various descriptors of the radiation therapy technique and disease free interval.