DYNAMIC COMPUTED TOMOGRAPHY OF THE PANCREAS IN NORMAL DOGS AND IN A DOG WITH PANCREATIC INSULINOMA

Authors

  • TOSHIE ISERI,

    1. The Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, the University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan,
    Search for more papers by this author
  • KAZUTAKA YAMADA,

    1. Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    Search for more papers by this author
  • KOUSAKU CHIJIWA,

    1. The Laboratory of Veterinary Medical Center, Graduate School of Agricultural and Life Sciences, the University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan
    Search for more papers by this author
  • RYOHEI NISHIMURA,

    1. The Laboratory of Veterinary Emergency Medicine, Graduate School of Agricultural and Life Sciences, the University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan,
    Search for more papers by this author
  • SATORU MATSUNAGA,

    1. The Laboratory of Veterinary Emergency Medicine, Graduate School of Agricultural and Life Sciences, the University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan,
    Search for more papers by this author
  • REINA FUJIWARA,

    1. The Laboratory of Veterinary Medical Center, Graduate School of Agricultural and Life Sciences, the University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan
    Search for more papers by this author
  • NOBUO SASAKI

    1. The Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, the University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan,
    Search for more papers by this author

Address correspondence and reprint requests to Dr. Nobuo Sasaki, at the above address. E-mail: asasaki@mail.ecc.u-tokyo.ac.jp

Abstract

To establish optimal imaging conditions for enhanced computed tomography (CT) for canine pancreatic tumors, 10 healthy beagles were subjected to dynamic CT. This technique was then applied to a dog with suspected insulinoma. The changes in mean peak enhancement and the delay time of the aorta and pancreas were determined. In normal beagles, maximal arterial and pancreatic CT enhancement was observed at 15±2 s (795±52 Housfield unit [HU]) and 28±9 s (118±16 HU) after contrast medium injection, respectively. Multiphase enhanced CT was performed in a pug with suspected insulinoma using the CT protocol defined for the normal beagles with some parameters modified; the images were acquired at the arterial (14 s after contrast medium injection), pancreatic (after 28 s), and equilibrium (after 90 s) phases; scanning was followed by exploratory laparotomy. CT images were characterized by an enhanced mass in the left pancreatic lobe at the arterial phase, during which the difference between the CT values of the mass and normal pancreas was the highest. Histopathologic diagnosis of the pancreatic mass was insulinoma. Thus, it appears that enhanced CT imaging can be used to delineate the pancreas from a pancreatic mass, and it may be helpful in deciding the need for surgery.

Ancillary