A NINE-DAY ACCELERATED RADIATION PROTOCOL FOR FELINE SQUAMOUS CELL CARCINOMA
Article first published online: 23 AUG 2007
Veterinary Radiology & Ultrasound
Volume 48, Issue 5, pages 482–485, September–October 2007
How to Cite
FIDEL, J. L., SELLON, R. K., HOUSTON, R. K. and WHEELER, B. A. (2007), A NINE-DAY ACCELERATED RADIATION PROTOCOL FOR FELINE SQUAMOUS CELL CARCINOMA. Veterinary Radiology & Ultrasound, 48: 482–485. doi: 10.1111/j.1740-8261.2007.00283.x
- Issue published online: 23 AUG 2007
- Article first published online: 23 AUG 2007
- Received October 3, 2006; accepted for publication March 15, 2007.
- accelerated therapy;
- oral tumors;
- squamous cell carcinoma
Nine cats with oral squamous cell carcinoma were treated with an accelerated radiation protocol (14 fractions of 3.5 Gy in 9 days). Radiation was administered twice daily with a 6 hour break between treatments. Median overall survival was 86±110 days. Median survival for cats with a partial response (n=6) was 60±7 days, while median survival for cats with a complete response (n=3) was 298±187 days (P=0.0639). The accelerated protocol was well tolerated and toxicity in the early and late period was manageable in all cats. Further modification of the protocol is warranted to extend survival.