SKELETAL LESIONS OF HISTIOCYTIC SARCOMA IN NINETEEN DOGS
Article first published online: 22 OCT 2007
© Copyright 2007 by the American College of Veterinary Radiology
Veterinary Radiology & Ultrasound
Volume 48, Issue 6, pages 539–543, November–December 2007
How to Cite
SCHULTZ, R. M., PUCHALSKI, S. M., KENT, M. and MOORE, P. F. (2007), SKELETAL LESIONS OF HISTIOCYTIC SARCOMA IN NINETEEN DOGS. Veterinary Radiology & Ultrasound, 48: 539–543. doi: 10.1111/j.1740-8261.2007.00292.x
- Issue published online: 22 OCT 2007
- Article first published online: 22 OCT 2007
- Received March 22, 2007; accepted for publication April 25, 2007.
- histiocytic sarcoma;
- malignant histiocytosis;
The purpose of this study was to describe the clinical and radiographic findings in dogs with bone lesions secondary to histiocytic sarcoma. Nineteen dogs with radiographically identified bone lesions that were histologically diagnosed as histiocytic sarcoma were assessed. The medical records, all available radiographs and histologic sections were reviewed retrospectively. Dogs were subcategorized into localized or disseminated histiocytic sarcoma groups. Golden Retrievers or Rottweilers greater than 5 years of age, with a history of lameness or neurologic deficits localized to the spinal cord was the most common presentation. Fifteen of 19 dogs had a radiographically detectable soft tissue mass associated with bone destruction. The bone lesions had aggressive characteristics and the sites of involvement included periarticular bones (n=11), vertebrae (n=6), proximal humerus (n=5), and rib (n=2). Fifteen of 19 dogs had disseminated histiocytic sarcoma, and four had localized histiocytic sarcoma. All Rottweilers had disseminated histiocytic sarcoma. Histiocytic sarcoma should be considered as a differential diagnosis for aggressive periarticular, vertebral, or proximal humeral bone lesions identified on radiographs. The index of suspicion should be increased in greater than 5-year-old Golden Retrievers and Rottweilers when a soft tissue mass is associated with the bone lesion on radiographs or myelography. Bone involvement with histiocytic sarcoma, and the Rottweiler breed, was associated with the disseminated form of the disease.