*Equally contributed to this work as co-first authors.
POSITRON EMISSION TOMOGRAPHY FEATURES OF CANINE NECROTIZING MENINGOENCEPHALITIS
Version of Record online: 27 OCT 2008
© Copyright 2008 by the American College of Veterinary Radiology
Veterinary Radiology & Ultrasound
Volume 49, Issue 6, pages 595–599, November/December 2008
How to Cite
EOM, K.-D., LIM, C.-Y., GU, S.-H., KANG, B.-T., KIM, Y.-B., JANG, D.-P., WOO, E.-J., KIM, D., CHO, Z.-H. and PARK, H.-M. (2008), POSITRON EMISSION TOMOGRAPHY FEATURES OF CANINE NECROTIZING MENINGOENCEPHALITIS. Veterinary Radiology & Ultrasound, 49: 595–599. doi: 10.1111/j.1740-8261.2008.00437.x
This research was supported by the SRC/ERC program (R11-2002-103) and a grant (M103KV010026-07K2201-02610) from the Brain Research Center of the 21st Century Frontier Research Program funded by the Ministry of Science and Technology, the Republic of Korea.
- Issue online: 27 OCT 2008
- Version of Record online: 27 OCT 2008
- Received December 29, 2007; accepted for publication April 2, 2008.
- fluorine-18 fluorodeoxyglucose positron emission tomography;
- magnetic resonance imaging;
- necrotizing meningoencephalitis
A Yorkshire terrier and a Chihuahua were referred for acute onset, generalized tonic-clonic seizures and were suspected to have meningoencephalitis based on magnetic resonance (MR) imaging findings. Brain lesions appeared hyperintense with T2-weighted imaging and hypointense with T1-weighted imaging, and were characteristic of necrotizing meningoencephalitis. Both dogs were diagnosed with necrotizing meningoencephalitis based on pathologic findings. Fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) was performed on both animals before euthanasia with the permission of the owner. In FDG-PET images, these lesions seen in MR images were characterized by multifocal or diffuse hypometabolism. Our FDG-PET results provided evidence of glucose hypometabolism in areas of necrosis and cavitation associated with necrotizing meningoencephalitis. FDG-PET has the potential to provide valuable diagnostic information in dogs with suspected necrotizing encephalitis.