Presented in part at the American College of Veterinary Internal Medicine Annual Meeting, San Antonio, TX, June 2008.
RELATIONSHIP BETWEEN PROSTATOMEGALY, PROSTATIC MINERALIZATION, AND CYTOLOGIC DIAGNOSIS
Article first published online: 26 FEB 2009
© 2009 American College of Veterinary Radiology
Veterinary Radiology & Ultrasound
Volume 50, Issue 2, pages 167–171, March/April 2009
How to Cite
BRADBURY, C. A., WESTROPP, J. L. and POLLARD, R. E. (2009), RELATIONSHIP BETWEEN PROSTATOMEGALY, PROSTATIC MINERALIZATION, AND CYTOLOGIC DIAGNOSIS. Veterinary Radiology & Ultrasound, 50: 167–171. doi: 10.1111/j.1740-8261.2009.01510.x
- Issue published online: 26 FEB 2009
- Article first published online: 26 FEB 2009
- Received July 30, 2008; accepted for publication September 25, 2008.
- prostatic mineralization;
Canine prostatic disease is commonly evaluated with abdominal ultrasound and radiographs. Mineralization of the prostate is often reported, but the clinical relevance of this finding is currently not known. The purpose of this study was to characterize the relationship between ultrasonographic and radiographic prostate mineralization and the final diagnosis. Medical records of 55 dogs with evidence of prostatomegaly or prostatic mineralization and a cytologic diagnosis were evaluated. Radiographs and ultrasound images were assessed for caudal retroperitoneal lymphadenopathy, vertebral lesions, or other signs of metastasis, and mineralization was assessed semiquantitatively. Twenty-two of 55 (40%) dogs had prostatic neoplasia. Regarding neoplasia, mineralization in neutered dogs had a positive predictive value (PPV) of 100%, a negative predictive value (NPV) of 50%, and a sensitivity and specificity of 84% and 100%, respectively. Mineralization in intact dogs had a PPV of 22%, an NPV of 96%, and a sensitivity and specificity of 67% and 77%, respectively. All neutered dogs with prostatomegaly but not prostatic neoplasia had bacterial prostatitis and were castrated within the previous 3 months. Intact dogs with prostatomegaly and mineralization but not neoplasia had paraprostatic cysts (n=3), benign prostatic hyperplasia (n=2) or prostatitis (n=2). Mineralization score was not indicative of neoplasia. In conclusion, neutered dogs with prostatic mineralization were very likely to have prostatic neoplasia. Intact dogs were unlikely to have prostatic neoplasia if no mineralization was found on radiographs or ultrasound.