PULMONARY ANGIOGRAPHY WITH 64-MULTIDETECTOR-ROW COMPUTED TOMOGRAPHY IN NORMAL DOGS

Authors

  • RANDI DREES,

    1. Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Linden Drive 2015, Madison, WI 53706
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  • ALEX FRYDRYCHOWICZ,

    1. Department of Radiology, School of Medicine and Public Health, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI 53792
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  • NICHOLAS S. KEULER,

    1. Department of Statistics, University of Wisconsin-Madison, 1300 University Avenue, Madison, WI 53706.
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  • SCOTT B. REEDER,

    1. Department of Radiology, School of Medicine and Public Health, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI 53792
    2. Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI 53792
    3. Biomedical Engineering and Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI 53792
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  • REBECCA JOHNSON

    1. Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Linden Drive 2015, Madison, WI 53706
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  • This project was funded by the Companion Animal Fund of the University of Wisconsin-Madison. Rebecca Johnson is supported by Grant 1UL1RR025011 from the Clinical and Translational Science Award (CTSA) program of the National Center for Research Resources (NCRR), National Institutes of Health (NIH).

Address correspondence and reprint requests to Dr. Randi Drees, at the above address. E-mail: drees@svm.vetmed.wisc.edu

Abstract

Pulmonary angiography using 64-multidetector-row computed tomography (MDCT) was used to evaluate pulmonary artery anatomy, and determine the sensitivity of pulmonary artery segment visualization in four Beagle dogs using images reconstructed to 0.625 mm and retro-reconstructed to 1.25 and 2.5 mm slice thickness. Morphologically, characteristic features included a focal narrowing in the right cranial pulmonary artery in all dogs, which should not be mistaken as stenosis. While the right cranial pulmonary artery divided into two equally sized branches that were tracked into the periphery of the lung lobe in all dogs, only a single left cranial (cranial portion) lobar artery was present. Compared with 1.25 and 2.5 mm retro-reconstructions, 0.625 mm reconstructions allowed for detection of significantly (P≤0.05) more pulmonary artery segments and sharper depiction of vessel margins. Clinical applications such as prevalence and significance of diameter changes, and detection of pulmonary arterial thrombembolism on lobar and sublobar level, using pulmonary angiography with 64-MDCT applying 0.625 mm reconstruction slice thickness remain to be established.

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