Presented as a poster with abstract at the Annual Scientific Meeting of the ACVR, Albuquerque, NM, October 11–15, 2011.
MAGNETIC RESONANCE IMAGING OF CANINE MAST CELL TUMORS
Version of Record online: 4 DEC 2011
© 2011 Veterinary Radiology & Ultrasound
Veterinary Radiology & Ultrasound
Volume 53, Issue 2, pages 167–173, March / April 2012
How to Cite
Pokorny, E., Hecht, S., Sura, P. A., LeBlanc, A. K., Phillips, J., Conklin, G. A., Haifley, K. A. and Newkirk, K. (2012), MAGNETIC RESONANCE IMAGING OF CANINE MAST CELL TUMORS. Veterinary Radiology & Ultrasound, 53: 167–173. doi: 10.1111/j.1740-8261.2011.01897.x
- Issue online: 19 MAR 2012
- Version of Record online: 4 DEC 2011
- Manuscript Accepted: 24 OCT 2011
- Manuscript Received: 14 AUG 2011
- mast cell tumor;
Mast cell tumors (MCT) are the most common cutaneous tumors in dogs. Our purpose was to describe the magnetic resonance (MR) imaging characteristics of cutaneous MCT and to identify imaging characteristics that allow differentiation of metastatic from normal lymph nodes. Eight dogs with a total of nineMCT were imaged as were their presumed draining and associated contralateral lymph nodes. The signal intensity of tumors and lymph nodes was compared to adjacent musculature. On T2-W images, 7/9 MCT were hyperintense to muscle and 2/9 were isointense. On T1-W images, 8/9 MCT were isointense and 1/9 were mildly hypointense. All tumors were strongly contrast enhancing; 5/9 were homogeneous and 4/9 heterogeneous in their enhancement patterns. Six lymph node pairs were included in the evaluation (five sentinel lymph nodes with metastases, one without, and six contralateral lymph nodes). Metastatic lymph nodes were significantly larger than their contralateral lymph nodes (P = 0.039). All lymph nodes were isointense on T1-W images and hyperintense on T2-W images. 5/5 metastatic and 2/7 normal lymph nodes were heterogeneously T2-hyperintense. All lymph nodes were moderately to strongly contrast enhancing. 4/5 metastatic and 2/7 normal lymph nodes had heterogeneous enhancement patterns. While heterogeneity was more common in metastatic than in normal lymph nodes, this difference was not significant (P = 0.058 for T2-W images; P = 0.234 for postcontrast images). MR imaging may be useful in the presurgical evaluation and clinical staging of cutaneous MCT.