This study was funded by an Internal Seed Grant, Tufts Cummings School of Veterinary Medicine.
COMPARISON BETWEEN CLINICAL, ULTRASOUND, CT, MRI, AND PATHOLOGY FINDINGS IN DOGS PRESENTED FOR SUSPECTED THYROID CARCINOMA
Article first published online: 18 SEP 2012
© 2012 Veterinary Radiology & Ultrasound
Veterinary Radiology & Ultrasound
Volume 54, Issue 1, pages 61–70, January/February 2013
How to Cite
Taeymans, O., Penninck, D. G. and Peters, R. M. (2013), COMPARISON BETWEEN CLINICAL, ULTRASOUND, CT, MRI, AND PATHOLOGY FINDINGS IN DOGS PRESENTED FOR SUSPECTED THYROID CARCINOMA. Veterinary Radiology & Ultrasound, 54: 61–70. doi: 10.1111/j.1740-8261.2012.01966.x
- Issue published online: 7 JAN 2013
- Article first published online: 18 SEP 2012
- Manuscript Accepted: 13 JUN 2012
- Manuscript Received: 9 MAR 2012
- Internal Seed Grant
- Tufts Cummings School of Veterinary Medicine
- carotid body tumor;
This study compares clinical, ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and pathology findings in 16 prospectively, and seven retrospectively recruited dogs presented for suspected thyroid carcinoma. Of these, 17 were confirmed thyroid carcinoma, while six were initially misdiagnosed. These included four carotid body tumors, one para-esophageal abscess, and one undifferentiated squamous cell carcinoma. Thyroid carcinomas occurred in older dogs without evidence of sex predilection, and were more often unilateral. All were large, heterogeneous, moderately to strongly vascularized, and most commonly contained areas of dystrophic mineralization and/or fluid accumulations. On MRI, thyroid carcinomas appeared hyperintense compared to surrounding musculature in all imaging sequences used, while on CT they had a lower attenuation value than normal thyroid gland tissue. Histologically confirmed tumor capsule disruption with invasion of the surrounding structures was most commonly detected with MRI. Palpation was not an accurate predictor of locally invasive vs. well-encapsulated masses. Computed tomography had the highest specificity (100%) and MRI had the highest sensitivity (93%) in diagnosing thyroid carcinoma, while ultrasound had considerably lower results. We conclude that ultrasound is adequate for use as a screening tool for dogs with suspected thyroid carcinoma, but recommend either CT or MRI for preoperative diagnosis and staging.