Using data from a representative sample (N = 1,026) of married workers in Singapore, this study examined potential family-to-work spillover relationships among marital distress, health and mental health, and work satisfaction. Results from structural equation modeling analysis showed that marital distress was a significant predictor of depressive symptoms, health, and work satisfaction. Health was not related to work satisfaction. Depression acted as an indirect link between marital distress and work satisfaction. No major gender differences emerged from the regression analysis, and approximately 40% of the variance in work satisfaction was explained by the model. Results suggest that marriage-to-work spillover is real and costly for families, organizations, and governments.