The past decade brought a remarkable increase in the number and quality of biosocial studies of family processes. The current review summarizes recent advances in biosocial family research by providing key exemplars of emerging research paradigms. Research in the past decade has substantiated the claim in the previous Decade Review (Booth, Carver, & Granger, 2000) that bidirectional influences between all levels of analysis are paramount. There is an emerging consensus that integrating factors at multiple biological and social levels is highly informative. Because ignoring biological factors often will underestimate mediating or moderating mechanisms, the review provides recommendations for biosocial family research. We also highlight the need for researchers who understand complex family environments to lend their expertise to biosocial studies.