Endocrine disruptor issues in Japan

Authors

  • Taisen Iguchi,

    Corresponding author
    1. Center for Integrative Bioscience, Okazaki National Research Institutes, Okazaki, Core Research for Evolutional Science and Technology, Japan Science and Technology, Kawaguchi, Japan
      Center for Integrative Bioscience, National Institute for Basic Biology, Okazaki National Research Institutes, 38 Nishigonaka, Myodaiji, Okazaki 444–8585, Japan. taisen@nibb.ac.jp
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  • Manabu Sumi,

    1. Environmental Health and Safety Division, Environmental Health Department, Ministry of the Environment, Tokyo, Japan
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  • Shinsuke Tanabe

    1. Center for Marine Environmental Studies, Ehime University, Matsuyama, Japan
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Center for Integrative Bioscience, National Institute for Basic Biology, Okazaki National Research Institutes, 38 Nishigonaka, Myodaiji, Okazaki 444–8585, Japan. taisen@nibb.ac.jp

Abstract

ABSTRACT  Monitoring of environmental chemicals in Japan has revealed that several endocrine active chemicals are in river water, sediments, and wildlife as well as in the human umbilical cord. In 2001, risk assessments of tributyltin and nonylphenol have been conducted by the Ministry of the Environment, Japan. Risk assessments of di(2-ethylhexyl)phthalate and di-isononyl phthalate have also been performed by the Ministry of Health, Labour and Welfare using a toxicological point of view in 2001. In this review, an overview of recent progress in endocrine disruptor research in Japan will be provided.

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