Disseminated tuberculosis complicating anti-TNF-α treatment

Authors


*D. Papaioannides, el. Venizelou 13, 19004 Spata, Greece
Fax: +30 2106630113
Email: dipapaio@otenet.gr

Summary

An unusually large number of cases of tuberculosis, often of miliary or disseminated form, have been reported in patients receiving infliximab therapy for rheumatoid arthritis or Crohn's disease. We describe a patient with rheumatoid arthritis who was treated with infliximab and became systemically ill with Mycobacterium tuberculosis-disseminated infection. Patients who are candidates for treatment with tumour necrosis factor-alfa inhibitors should be evaluated for the presence of latent or active M. tuberculosis infection.

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