The mean platelet volume in patients with obesity

Authors

  • E. Coban,

    Corresponding author
    1. Department of Internal Medicine,1Division of Endocrinology and Metabolism,2Department of Biochemistry,3Akdeniz University Faculty of Medicine, Antalya, Turkey
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  • 1 M. Ozdogan,

    1. Department of Internal Medicine,1Division of Endocrinology and Metabolism,2Department of Biochemistry,3Akdeniz University Faculty of Medicine, Antalya, Turkey
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  • 1 G. Yazicioglu,

    1. Department of Internal Medicine,1Division of Endocrinology and Metabolism,2Department of Biochemistry,3Akdeniz University Faculty of Medicine, Antalya, Turkey
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  • and 2 F. Akcit 3

    1. Department of Internal Medicine,1Division of Endocrinology and Metabolism,2Department of Biochemistry,3Akdeniz University Faculty of Medicine, Antalya, Turkey
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*Dr Erkan Coban, MD, Akdeniz University Faculty of Medicine, Department of Internal Medicine, 07070 Antalya, Turkey
Tel.: + 90 242 2274343/55139
Fax: + 90 242 2274490
Email: ecoban@akdeniz.edu.tr

Summary

Mean platelet volume (MPV), a determinant of platelet function, is a newly emerging risk factor for atherothrombosis. The present study was designed to evaluate MPV in patients with obesity compared with non-obese control subjects. We selected 100 non-obese subjects and 100 subjects with obesity [body mass index (BMI) ≥30 kg/m2] matched for age and gender. The MPV was significantly higher in obese group than in non-obese control group (10.3 ± 1.2 vs. 9.0 ± 0.8 fl, p < 0.01). MPV was positively correlated with BMI in obese group (p < 0.05). Increased MPV may be a possible cause for increased cardiovascular risk in patients with obesity.

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