Cola-induced hypokalaemia: pathophysiological mechanisms and clinical implications
Version of Record online: 13 MAY 2009
© 2009 Blackwell Publishing Ltd
International Journal of Clinical Practice
Volume 63, Issue 6, pages 900–902, June 2009
How to Cite
Tsimihodimos, V., Kakaidi, V. and Elisaf, M. (2009), Cola-induced hypokalaemia: pathophysiological mechanisms and clinical implications. International Journal of Clinical Practice, 63: 900–902. doi: 10.1111/j.1742-1241.2009.02051.x
- Issue online: 13 MAY 2009
- Version of Record online: 13 MAY 2009
Background/Aims: The consumption of soft drinks has increased considerably during the last decades. Among them, the cola-based preparations are possibly the refreshments with the largest sales worldwide. In addition to the possible detrimental effects of moderate, chronic cola consumption, it has been proposed that the consumption of large amounts of cola-based soft drinks may result in severe hypokalaemia.
Methods: In this review, we discuss the clinical significance of these disturbances and summarise the pathophysiological mechanism that may underlie the development of this rare, but potentially severe, side effect.
Results/Conclusion: Several lines of evidence suggest that the chronic consumption of large amounts of cola soft drinks may adversely affect potassium homeostasis and result in potentially severe conditions such as hypokalaemic myopathy.