• 1
    Carrillo N & Ceccarelli EA (2003) Open questions in ferredoxin-NADP+ reductase catalytic mechanism. Eur J Biochem 270, 19001915.
  • 2
    Ziegler GA & Schulz GE (2000) Crystal structures of adrenodoxin reductase in complex with NADP+ and NADPH suggesting a mechanism for the electron transfer of an enzyme family. Biochemistry 39, 1098610995.
  • 3
    Karplus PA & Faber HR (2004) Structural aspects of plant ferredoxin:NADP+ oxidoreductases. Photosynth Res 81, 303315.
  • 4
    Bossi RT, Aliverti A, Raimondi D, Fischer F, Zanetti G, Ferrari D, Tahallah N, Maier CS, Heck AJ, Rizzi M et al. (2002) A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase. Biochemistry 41, 88078818.
  • 5
    Pennati A, Razeto A, de Rosa M, Pandini V, Vanoni MA, Mattevi A, Coda A, Aliverti A & Zanetti G (2006) Role of the His57–Glu214 ionic couple located in the active site of Mycobacterium tuberculosis FprA. Biochemistry 45, 87128720.
  • 6
    Orr GA & Blanchard JS (1984) High-performance ion-exchange separation of oxidized and reduced nicotinamide adenine dinucleotides. Anal Biochem 142, 232234.
  • 7
    Wong P, Bachki A, Banerjee K & Leyland-Jones B (2002) Identification of N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-5-carboxamide as components in urine extracts of individuals consuming coffee. J Pharm Biomed Anal 30, 773780.
  • 8
    Chang MLW & Johnson BC (1959) N-Methyl-4-pyridone-5-carboxamide, a new major normal metabolite of nicotinic acid in rat urine. J Biol Chem 234, 18171821.
  • 9
    Scriven EFV (1984) Pyridines and their benzo derivatives: (ii) reactivity at ring atoms. In Comprehensive Heterocycle Chemistry, Vol. 2 (Katritzky AR & Rees CW, eds), pp. 167168. Pergamon Press, Oxford, UK.
  • 10
    Fischer F, Raimondi D, Aliverti A & Zanetti G (2002) Mycobacterium tuberculosis FprA, a novel bacterial NADPH-ferredoxin reductase. Eur J Biochem 269, 30053013.
  • 11
    Pandini V, Caprini G, Thomsen N, Aliverti A, Seeber F & Zanetti G (2002) Ferredoxin-NADP+ reductase and ferredoxin of the protozoan parasite Toxoplasma gondii interact productively in vitro and in vivo. J Biol Chem 277, 4846348471.
  • 12
    Milani M, Balconi E, Aliverti A, Mastrangelo E, Seeber F, Bolognesi M & Zanetti G (2007) Ferredoxin-NADP+ reductase from Plasmodium falciparum undergoes NADP+-dependent dimerization and inactivation: functional and crystallographic analysis. J Mol Biol 367, 501513.
  • 13
    Aliverti A, Jansen T, Zanetti G, Ronchi S, Herrmann RG & Curti B (1990) Expression in Escherichia coli of ferredoxin:NADP+ reductase from spinach. Bacterial synthesis of the holoflavoprotein and of an active enzyme form lacking the first 28 amino acid residues of the sequence. Eur J Biochem 191, 551555.
  • 14
    Deng Z, Aliverti A, Zanetti G, Arakaki AK, Ottado J, Orellano EG, Calcaterra NB, Ceccarelli EA, Carrillo N & Karplus PA (1999) A productive NADP+ binding mode of ferredoxin-NADP+ reductase revealed by protein engineering and crystallographic studies. Nat Struct Biol 6, 847853.
  • 15
    Soares S, Thompson M, White T, Isbell A, Yamasaki M, Prakash Y, Lund FE, Galione A & Chini EN (2006) NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells. Am J Physiol Cell Physiol 292, C227C239.
  • 16
    Meijers R, Morris RJ, Adolph HW, Merlii A, Lamzin VS & Cedergren-Zeppezauer ES (2001) On the enzymatic activation of NADH. J Biol Chem 276, 93169321.
  • 17
    Aliverti A, Deng Z, Ravasi D, Piubelli L, Karplus PA & Zanetti G (1998) Probing the function of the invariant glutamyl residue 312 in spinach ferredoxin-NADP+ reductase. J Biol Chem 273, 3400834015.
  • 18
    Röhrich RC, Englert N, Troschke K, Reichenberg A, Hintz M, Seeber F, Balconi E, Aliverti A, Zanetti G, Köhler U et al. (2005) Reconstitution of an apicoplast-localised electron transfer pathway involved in the isoprenoid biosynthesis of Plasmodium falciparum. FEBS Lett 579, 64336438.
  • 19
    Chen PS, Toribara TY & Warber H (1956) Microdetermination of phosphorus. Anal Chem 28, 17561758.
  • 20
    Wang ZX, Kumar NR & Srivastava DK (1992) A novel spectroscopic titration method for determining the dissociation constant and stoichiometry of protein–ligand complex. Anal Biochem 206, 376381.